Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 4.8μM | Low |
| 8 hr | 4.8μM | Low |
| 24 hr | 4.8μM | Low |
| 2 hr | 24μM | Middle |
| 8 hr | 24μM | Middle |
| 24 hr | 24μM | Middle |
| 2 hr | 120μM | High |
| 8 hr | 120μM | High |
| 24 hr | 120μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 4.8μM | Low |
| 8 hr | 4.8μM | Low |
| 24 hr | 4.8μM | Low |
| 2 hr | 24μM | Middle |
| 8 hr | 24μM | Middle |
| 24 hr | 24μM | Middle |
| 2 hr | 120μM | High |
| 8 hr | 120μM | High |
| 24 hr | 120μM | High |