Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 1μM | Low |
| 8 hr | 1μM | Low |
| 24 hr | 1μM | Low |
| 2 hr | 5μM | Middle |
| 8 hr | 5μM | Middle |
| 24 hr | 5μM | Middle |
| 2 hr | 25μM | High |
| 8 hr | 25μM | High |
| 24 hr | 25μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 1μM | Low |
| 8 hr | 1μM | Low |
| 24 hr | 1μM | Low |
| 2 hr | 5μM | Middle |
| 8 hr | 5μM | Middle |
| 24 hr | 5μM | Middle |
| 2 hr | 25μM | High |
| 8 hr | 25μM | High |
| 24 hr | 25μM | High |