Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 0.28μM | Low |
| 8 hr | 0.28μM | Low |
| 24 hr | 0.28μM | Low |
| 2 hr | 1.4μM | Middle |
| 8 hr | 1.4μM | Middle |
| 24 hr | 1.4μM | Middle |
| 2 hr | 7μM | High |
| 8 hr | 7μM | High |
| 24 hr | 7μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 0.28μM | Low |
| 8 hr | 0.28μM | Low |
| 24 hr | 0.28μM | Low |
| 2 hr | 1.4μM | Middle |
| 8 hr | 1.4μM | Middle |
| 24 hr | 1.4μM | Middle |
| 2 hr | 7μM | High |
| 8 hr | 7μM | High |
| 24 hr | 7μM | High |