Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 4μM | Low |
| 8 hr | 4μM | Low |
| 24 hr | 4μM | Low |
| 2 hr | 20μM | Middle |
| 8 hr | 20μM | Middle |
| 24 hr | 20μM | Middle |
| 2 hr | 100μM | High |
| 8 hr | 100μM | High |
| 24 hr | 100μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 4μM | Low |
| 8 hr | 4μM | Low |
| 24 hr | 4μM | Low |
| 2 hr | 20μM | Middle |
| 8 hr | 20μM | Middle |
| 24 hr | 20μM | Middle |
| 2 hr | 100μM | High |
| 8 hr | 100μM | High |
| 24 hr | 100μM | High |