Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 6μM | Low |
| 8 hr | 6μM | Low |
| 24 hr | 6μM | Low |
| 2 hr | 30μM | Middle |
| 8 hr | 30μM | Middle |
| 24 hr | 30μM | Middle |
| 2 hr | 150μM | High |
| 8 hr | 150μM | High |
| 24 hr | 150μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 6μM | Low |
| 8 hr | 6μM | Low |
| 24 hr | 6μM | Low |
| 2 hr | 30μM | Middle |
| 8 hr | 30μM | Middle |
| 24 hr | 30μM | Middle |
| 2 hr | 150μM | High |
| 8 hr | 150μM | High |
| 24 hr | 150μM | High |