Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 10μM | Low |
| 8 hr | 10μM | Low |
| 24 hr | 10μM | Low |
| 2 hr | 50μM | Middle |
| 8 hr | 50μM | Middle |
| 24 hr | 50μM | Middle |
| 2 hr | 250μM | High |
| 8 hr | 250μM | High |
| 24 hr | 250μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 10μM | Low |
| 8 hr | 10μM | Low |
| 24 hr | 10μM | Low |
| 2 hr | 50μM | Middle |
| 8 hr | 50μM | Middle |
| 24 hr | 50μM | Middle |
| 2 hr | 250μM | High |
| 8 hr | 250μM | High |
| 24 hr | 250μM | High |