Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 16μM | Low |
| 8 hr | 16μM | Low |
| 24 hr | 16μM | Low |
| 2 hr | 80μM | Middle |
| 8 hr | 80μM | Middle |
| 24 hr | 80μM | Middle |
| 2 hr | 400μM | High |
| 8 hr | 400μM | High |
| 24 hr | 400μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 16μM | Low |
| 8 hr | 16μM | Low |
| 24 hr | 16μM | Low |
| 2 hr | 80μM | Middle |
| 8 hr | 80μM | Middle |
| 24 hr | 80μM | Middle |
| 2 hr | 400μM | High |
| 8 hr | 400μM | High |
| 24 hr | 400μM | High |