Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 12μM | Low |
| 8 hr | 12μM | Low |
| 24 hr | 12μM | Low |
| 2 hr | 60μM | Middle |
| 8 hr | 60μM | Middle |
| 24 hr | 60μM | Middle |
| 2 hr | 300μM | High |
| 8 hr | 300μM | High |
| 24 hr | 300μM | High |

| Time | Dose | Dose Level |
|---|---|---|
| 2 hr | 12μM | Low |
| 8 hr | 12μM | Low |
| 24 hr | 12μM | Low |
| 2 hr | 60μM | Middle |
| 8 hr | 60μM | Middle |
| 24 hr | 60μM | Middle |
| 2 hr | 300μM | High |
| 8 hr | 300μM | High |
| 24 hr | 300μM | High |